Chaperone Function: The Orthodox View
نویسندگان
چکیده
منابع مشابه
Role of Molecular Interactions and Oligomerization in Chaperone Activity of Recombinant Acr from Mycobacterium tuberculosis
Background: The chaperone activity of Mycobacterium tuberculosis Acr is an important function that helps to prevent misfolding of protein substrates inside the host, especially in conditions of hypoxia. Objectives: The aim of this study was to establish the correlation of structure and function of recombinant Acr proteins both before and after ge...
متن کاملCo-expression of recombinant human nerve growth factor with trigger factor chaperone in E. coli
Nerve growth factor (NGF) is a neurotrophic factor that is functional in the survival, maintenance and differentiation of nervous system cells. This protein has three subunits, of which the beta subunit has the main activity. Its structure consists of a cysteine knot motif made up of beta strands linked by disulfide bonds. It can be used as a therapeutic agent in the treatment of many diseases....
متن کاملPurification and in vitro chaperone activity of a class I small heat-shock protein abundant in recalcitrant chestnut seeds.
A 20-kD protein has been purified from cotyledons of recalcitrant (desiccation-sensitive) chestnut (Castanea sativa) seeds, where it accumulates at levels comparable to those of major seed storage proteins. This protein, termed Cs smHSP 1, forms homododecameric complexes under nondenaturing conditions and appears to be homologous to cytosolic class I small heat-shock proteins (smHSPs) from plan...
متن کاملAging in Orthodox Seeds is a Problem
Seed deterioration is loss of seed quality, viability and vigor due to effect of adverse environmental factors. Many of our crops are reproduced through seeds, and throughout the world large quantities are produced, stored and transported. Seed ageing during storage may cause retardation of field establishment, and may eventually result in seedling abnormalities or even failure of emergence. Du...
متن کاملAging in Orthodox Seeds is a Problem
Seed deterioration is loss of seed quality, viability and vigor due to effect of adverse environmental factors. Many of our crops are reproduced through seeds, and throughout the world large quantities are produced, stored and transported. Seed ageing during storage may cause retardation of field establishment, and may eventually result in seedling abnormalities or even failure of emergence. Du...
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